Fat grafting or Sculptra injections take a little longer, but the procedure is less invasive and might last longer. Small amounts of real or synthetic fat are gradually injected into layers of the cheek using a fine needle. You will need several procedures before you get the chubby cheeks you desire. Sculptra injections are generally tolerated well and come with a low risk of complications. Fat grafting and silicone injections can be a bit riskier, though.Note that you may need to get further treatments after a few years. Such is the case with Sculptra, which often needs replacement after two years.