1. Despite indicates an illogical occurrence.
We had a good time despite the bad weather.
2. In spite of has the same meaning and usage as despite.
We had a good time in spite of the bad weather.
Fact
In 1902, the coat hanger was invented Albert Parkhouse who was frustrated at the lack of hooks available to hang up his coat at work. His company thought it was a good idea and patented the invention and unfortunately, Parkhouse never received any money for his idea
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